Bioventus Launches DUROLANE in Malaysia
HOOFDDORP, THE NETHERLANDS – January 29, 2019 – Bioventus, a global leader in orthobiologic solutions, is launching DUROLANE, its single-injection joint-fluid osteoarthritis (OA) treatment, in Malaysia and has selected Athrotech as its exclusive distribution partner for the market.
OA involves the breakdown, or degeneration, of cartilage and the synovial fluid that cushions and lubricates joint tissues. It’s estimated that up to 20% of the adult population of Malaysia suffers from osteoarthritis and the most common form of OA in the country is knee OA.1 Hyaluronic acid (HA)-based products like DUROLANE, help manage pain in the knees and hips of patients with OA.
“Athrotech is a great fit for Bioventus as we continue to grow in Asia and expand our reach with HA products like DUROLANE,” said Tony Bihl, CEO of Bioventus. “Malaysia is the fourth market in Asia where Bioventus has introduced DUROLANE, providing even more patients and physicians access to a proven pain reliever for knee OA.”
“We’re passionate about technologies that minimize risk, time, are helpful to patients and have uncompromising quality,” said Jeff Luah, Director, Athrotech. “DUROLANE is safe, patient injections can be done very quickly and it is a single injection product designed to provide powerful and long-lasting knee pain relief.”
“Athrotech has experience in the orthopedic field associated with OA as a disease state and we are pleased to offer them the exclusive distribution rights to DUROLANE,” said John Nosenzo, Chief Commercial Officer, Bioventus. “The market has a favorable mix of private, payer and self-pay patients and we expect to grow our business together for many years to come.”
DUROLANE is based on a natural, safe and proven technology process called NASHA®. This process yields stabilized (HA) which is a naturally occurring molecule that provides the lubrication and cushioning in a normal joint. It has been proven to provide greater reduction in OA knee pain versus Synvisc-One®2* and longer lasting pain relief versus a steroid injection3. DUROLANE is also safe for repeated courses of therapy. Repeated use of DUROLANE does not increase the incidence of adverse events.4
About Bioventus
Bioventus is an orthobiologics company that delivers clinically proven, cost-effective products that help people heal quickly and safely. Its mission is to make a difference by helping patients resume and enjoy active lives. The orthobiologic products from Bioventus include offerings for osteoarthritis, surgical and non-surgical bone healing. Built on a commitment to high quality standards, evidence-based medicine and strong ethical behavior, Bioventus is a trusted partner for physicians worldwide. For more information, visit www.BioventusGlobal.com and follow the company on Twitter @Bioventusglobal.
Bioventus, the Bioventus logo, and DUROLANE are registered trademarks of Bioventus LLC. NASHA is a registered trademark of Nestle Skin Health. Synvisc-One and Synvisc are registered trademarks of Genzyme Corporation.
Media Contact: Thomas Hill, , [email protected]
Summary of Indication for Use: Symptomatic treatment of mild to moderate knee or hip osteoarthritis. There are no known contraindications. You should not use DUROLANE if you have infections or skin disease at the injection site. DUROLANE has not been tested in pregnant or lactating women, or children. Risks can include transient pain, swelling and/or stiffness at the injection site. Indications presented are those approved in Malaysia; indications and product offerings vary by country. Consult with your local Bioventus representative for approved use within your region of interest. Full prescribing information can be found in product labeling, at www.DUROLANE.com.
References: 1. Arthritis Foundation of Malaysia website http://afm.org.my/wp/?p=77. Updated 2015. Accessed November 1, 2018. 2. McGrath AF, McGrath AM, Jessop ZM, et al. A comparison of intra-articular hyaluronic acid competitors in the treatment of mild to moderate knee osteoarthritis. J Arthritis. 2013; 2(1):108. doi:10.4172/2167-7921.1000108. 3. Leighton R, Åkermark C, Therrien R, et. al. NASHA hyaluronic acid vs methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial. Osteoarthritis Cartilage. 2014; 22(1):17-25. 4. DUROLANE [package insert]. Durham, NC: Bioventus LLC; 2017.
Bioventus Launches OSTEOMATRIX+® Biphasic Bone Graft
DURHAM, NC – January 15, 2019 – Bioventus, a global leader in orthobiologic solutions, is launching OSTEOMATRIX+, its next generation biphasic bone graft for use in bone remodeling in a variety of orthopaedic and spine applications. OSTEOMATRIX+ is a moldable bone graft substitute consisting of bovine collagen and biphasic, hydroxyapatite/ß-tricalcium phosphate granules designed to produce a reliable, porous scaffold and sustained osteoconductivity throughout the bone remodeling process.
The Bioventus research and development group led a cross functional team to develop OSTEOMATRIX+ which has more unique handling properties, including improved moldability, flexibility and versatility, than its predecessor.
“OSTEOMATRIX+ represents the first of several next generation products that will be added to the Bioventus portfolio in the next five years,” said Tony Bihl, CEO, Bioventus. “We will provide more diverse orthobiologic offerings for hospitals and efficacious solutions for both surgeons and their patients, as we continue to grow and serve these markets.”
OSTEOMATRIX+ is available now from distributors nationwide. Visit www.BioventusSurgical.com
to learn more.
About Bioventus
Bioventus is an orthobiologics company that delivers clinically proven, cost-effective products that help people heal quickly and safely. Its mission is to make a difference by helping patients resume and enjoy active lives. The orthobiologic products from Bioventus include offerings for osteoarthritis, surgical and non-surgical bone healing. Built on a commitment to high quality standards, evidence-based medicine and strong ethical behavior, Bioventus is a trusted partner for physicians worldwide. For more information, visit www.BioventusGlobal.com and follow the company on Twitter @Bioventusglobal.
Bioventus, the Bioventus logo and OSTEOMATRIX+ are registered trademarks of Bioventus LLC.
Media Contact: Thomas Hill, , [email protected]
Summary of Indications for Use
OSTEOMATRIX+ is a bone graft substitute intended for use in bony voids or gaps of the skeletal system not intrinsic to the stability of the bony structure. These osseous defects may be surgically created or result from traumatic injury to the bone. OSTEOMATRIX+ is indicated to be combined with autologous bone marrow aspirate and packed into osseous defects of the extremities, pelvis and posterolateral spine. When used in the posterolateral spine, OSTEOMATRIX+ is to be used as an autograft extender. The device resorbs and is replaced by host bone during the healing process.
Contraindications
OSTEOMATRIX+ is not designed or sold for any use except as indicated. Do not use OSTEOMATRIX+ in the presence of any contraindication. OSTEOMATRIX+ is contraindicated where the device is intended as structural support in the skeletal system. OSTEOMATRIX+ must not be used in patients with a history of anaphylaxis, history of multiple allergies, known allergies to bovine collagen, or patients that are being treated for desensitization to meat products. Other conditions representing contraindications include: Necrosis or infection at the graft site, Malignant tumors, Intra-articular implantations, Severe vascular or neurological disease proximal to the graft site, Hypercalcemia, abnormal calcium metabolism, Inflammatory bone disease such as osteomyelitis, Metabolic or systemic bone disorders that affect, bone or wound healing, Patients unwilling or incapable of following post-operative instructions.
Please refer to the package insert for a complete listing of contraindications, warnings and precautions, and instructions for use.
